Like most of us with PD, I have had problems with constipation. In the past, I was able to deal with this using a herbal laxative, fiber powder, prunes, hydration, and exercise. A few years ago I developed an ongoing problems with bloating that was not relieved by gas pills. My gastroenterologist (does my colonoscopies) had me start on Linzess about 2 years ago. Gross alert! My stools have consisted on mostly water for the last 6 months and the bloating had not improved.
After my last colonoscopy in December we revisited these problems. He told me there were new meds that he wanted me to try. I took Xifaxin-550 mg (an antibiotic) for two weeks and then started on Motegrity-2 mg five days ago. I have had multiple "normal" bowel movements every day. I had some headaches initially with both drugs and there is some dizziness, but it is well worth it for me. The motegrity is a 90 day prescription that I think I will be taking for 6 months and then decide with doc where to go from there. Meanwhile, my quality of life feels much improved!
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