DUOPATM, a gel formulation of
the drug carbidopa/levodopa that is delivered directly to the small intestine
through a surgically-placed tube, has been approved by the US Food and Drug
Administration (FDA) for the treatment of motor fluctuations in advanced
Parkinson's disease. The approval was announced yesterday by the drug’s
manufacturer, AbbVie, Inc.
This
new drug is a formulation of the gold-standard treatment carbidopa/levodopa. The
manufacturer states that DUOPATM uses the same active
ingredients as orally-administered carbidopa/levodopa, but is designed to
improve absorption and reduce off-times for people with advanced Parkinson's
disease by delivering the drug directly into the small intestine. DUOPATM is delivered for 16
continuous hours every day by a pump through a tube that requires a small
surgically-placed hole in the stomach.
What
does it mean? According to Kathleen M. Shannon, M.D., Chair of PDF's Medical
Policy Committee, this is a welcome advance for a subset of people living with
advanced Parkinson’s disease.
Learn
more by watching our short video and reading our official
statement.
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